The present invention provides crystalline forms, solvates and hydrates of 4-amino-2-butoxy-8-(3-(pyrrolidin-1-ylmethyl)benzyl)-7,8-dihydropteridin-6(5H)-one and methods of making.本發明提供4-胺基-2-丁氧基-8-(3-(吡咯啶-1-基甲基)苄基)-7,8-二氫喋啶-6(5H)-酮的結晶型、溶劑合物及水合物及製造方法。