Use of sulfated glycosaminoglycans for improving the bioavailability of Factor VIII

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专利权人:

CSL Behring GmbH

发明人:

Metzner, Hubert,Zollner, sabine

申请号：

AU2012318279

公开号：

AU2012318279A1

申请日:

2012.10.18

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

#$%^&*AU2012318279A120130502.pdf#####CSL BEARING GMBH 2011_MOO6_A182 HAU/kk 12.10.2012 5 Abstract The present invention relates to pharmaceutical preparations comprising one or more Factor Vill and a sulfated glycosaminoglycan for increasing the bioavailability of Factor VIll upon non-intravenous administration. The invention further relates to 10 the combined use of Factor VIII and a sulfated glycosaminoglycan for the treatment and prevention of bleeding disorders, whereby the bioavailability of Factor VIII is increased, and to a method for increasing the bioavailability after non-intravenous administration of Factor VIII by coadminstration of a sulfated glycosaminoglycan.

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