Ko Rii;Sadaharu Higuchi;Kazuo Sakurai;Masakazu Kobayashi;Hironori Ando;Shiro Takahara
发明人:
Ko Rii,Kazuo Sakurai,Masakazu Kobayashi,Hironori Ando,Sadaharu Higuchi,Shiro Takahara
申请号：
US14237763
公开号：
US09801929B2
申请日:
2012.07.13
申请国别(地区):
US
年份:
2017
代理人:
摘要：
An object of the present invention is to provide a drug and a method for effectively inducing donor-specific immune tolerance in a recipient in transplantation therapy. A complex of an siRNA for a costimulatory factor and schizophyllan is delivered to a Dectin-1 expressing cell which specifically recognizes schizophyllan to regulate the function of the Dectin-1 expressing cell, and therefore can induce immunosuppression effect as well as induce immune tolerance effectively.
