Davidson, Alan Hornsby,Donald, Alastair David Graham,Day, Francesca Ann,Moffat, David Festus Charles
申请号:
AU2007304022
公开号:
AU2007304022B2
申请日:
2007.09.14
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Compounds of formula (I) inhibit HDAC activity, wherein A, B and D independentlyrepresent =C- or =N-; W is a divalent radical -CH=CH- or CHCH-;R is a carboxylic acid group (-COOH), or an ester group which is hydrolysableby one or more intracellular carboxyesterase enzymes to a carboxylic acid group;R is the side chain of a natural or non-natural alpha amino acid; z is0 or 1; and Y, L, and X are as defined in the claims.