FERON, CHRISTIANE MARIE-PAULE SIMONE JEANNE,KEMMLER, STEFAN JOCHEN,KOWARIK, MICHAEL THOMAS,QUEBATTE, JULIEN LAURENT
申请号：
CA3002117
公开号：
CA3002117A1
申请日:
2016.10.19
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention discloses a conjugate comprising an antigen (for example a saccharide antigen) covalently linked to a Pseudomonas aeruginosa PcrV carrier protein comprising an amino acid sequence which is at least 80% identical to the sequence of SEQ ID NO:1-4, wherein the antigen is linked (either directly or through a linker) to an amino acid residue of the P. aeruginosa PcrV carrier protein. The invention also discloses Pseudomonas aeruginosa PcrV proteins that contain glycosylation site consensus sequences.
