An item of clothing is adapted to be worn against the skin and comprises at least one panel adapted to provide targeted compression of at least 20% of the total length of a specific surface vein in the body or adapted to provide targeted compression of at least 20% of a specific plexus of veins a specific lymphatic plexus drainage plexus or a collection of lymphatic vessels. The clothing is useful in a method of reducing recovery time in a human or other mammal after a period of activity and in a method of enhancing performance in particular sports performance in a human or other mammal. It may also improve the conditioning of the skin and aid lymphatic drainage and can be used in the treatment of certain medical conditions.
