Localization and characterization of flavivirus envelope glycoprotein cross-reactive epitopes and methods for their use

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专利权人:

发明人:

Gwong-Jen J. Chang,Wayne D. Crill

申请号：

US14659251

公开号：

US09650422B2

申请日:

2015.03.16

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Disclosed herein is a method for identifying flavivirus cross-reactive epitopes. Also provided are flavivirus E-glycoprotein cross-reactive epitopes and flavivirus E-glycoprotein cross-reactive epitopes having reduced or ablated cross-reactivity (and polypeptides comprising such epitopes), as well as methods of using these molecules to elicit an immune response against a flavivirus and to detect a flaviviral infection.

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中国工程科技知识中心

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http://www.ckcest.cn/home/