PROBLEM TO BE SOLVED: To provide a biocompatible polymer porous body capable of providing a cell structure exhibiting high cell number and high blood vessel number and a manufacturing method therefor, a biocompatible polymer bock and the cell structure.SOLUTION: According to the invention, there are provided a manufacturing method of a biocompatible polymer porous body including (a) a process of cooling a solution of a biocompatible polymer to a non-frozen state at temperature difference between a part having the highest liquid temperature and a part having the lowest liquid temperature in a solution of 2.5°C or less and the temperature of the part having the highest liquid temperature in the solution having the melting point of a solvent or lower, (b) a process of freezing the solution of the a biocompatible polymer obtained in the process (a), and (c) a process of lyophilizing the frozen biocompatible polymer obtained in the process (b). There are also provided a biocompatible polymer porous body, a biocompatible polymer block, and a cell structure.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】本発明の課題は、高い細胞数及び高い血管数を示す細胞構造体を提供することを可能とする生体親和性高分子多孔質体及びその製造方法、並びに生体親和性高分子ブロック及び細胞構造体を提供することである。【解決手段】本発明によれば、(a)溶液内で最も液温の高い部分の温度と溶液内で最も液温の低い部分の温度との差が2.5℃以下であり、かつ、溶液内で最も液温の高い部分の温度が溶媒の融点以下で、生体親和性高分子の溶液を、未凍結状態に冷却する工程、(b)工程(a)で得られた生体親和性高分子の溶液を凍結する工程、および(c)工程(b)で得られた凍結した生体親和性高分子を凍結乾燥する工程を含む生体親和性高分子多孔質体の製造方法;並びに生体親和性高分子多孔質体、生体親和性高分子ブロック及び細胞構造体が提供される。【選択図】なし
