The Provost; Fellows; Foundation Scholars; & the other members of Board; of the College of the Holy & Undiv. Trinity of Queen Elizabeth near Dublin
发明人:
申请号：
EP16173940.4
公开号：
EP3117832A1
申请日:
2009.01.29
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The present invention is directed to improved microbial antigen vaccines, pharmaceutical compositions, immunogenic compositions and antibodies and their use in the treatment of microbial infections, particularly those of bacterial origin, including Staphylococcal origin. Ideally, the present invention is directed to a recombinant staphylococcal MSCRAMM or MSCRAMM-like proteins, or fragment thereof, with reduced binding to its host ligand, for use in therapy.
