MIYATA, TOSHIO;KUROKAWA, KIYOSHI;TOKAI UNIVERSITY EDUCATIONAL SYSTEM
发明人:
申请号：
EP99938581.8
公开号：
EP1108434B1
申请日:
1999.08.23
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
Drugs for relieving carbonyl stress in the peritoneal cavity to be used in peritoneal dialysates which contain carbonyl compound-trapping agents as the active ingredient. Carbonyl compounds formed and accumulated during peritoneal dialysis are inactivated or eliminated by carbonyl compound-trapping agents such as aminoguanidine. Carbonyl compounds formed during the sterilization and storage of peritoneal dialysates are eliminated by preliminarily bringing into contact with the trapping agents. Further, addition of the trapping agents to peritoneal dialysates or circulation of the trapping agents by using a cartridge for trapping carbonyl compounds makes it possible to eliminate carbonyl compounds originating in the blood of the patients which flow into the peritoneal cavity as the dialysis proceeds. Thus, modification of proteins in the peritoneal cavity can be inhibited and peritoneal damage in association with peritoneal dialysis can be relieved.
