Lewis C. Cantley,Reuben J. Shaw,Nabeel Bardeesy,Ronald A. Depinho
申请号:
US13354953
公开号:
US20120122991A1
申请日:
2012.01.20
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to modulation of LKB1 or AMP kinase protein activity for treating disorders including diabetes and cancer. The invention also relates to screening for agents that modulate the activity of LKB1 or AMP kinase protein, which are useful in the treatment of diabetes and cancer, as well as preparing compounds for treatment of diabetes and cancer.