VAN LONKHUYZEN, DEREK,PEET, JESSE,RIZZI, SIMONE,CROLL, TRISTAN,UPTON, ZEE,SHOOTER, GARY, KEITH
申请号：
NZ59573110
公开号：
NZ595731A
申请日:
2010.03.19
申请国别(地区):
NZ
年份:
2013
代理人:
摘要：
595731 Discloses a method of screening for a therapeutic agent effective for the treatment of a transglutaminase (TG)-associated disorder, disease and/or condition. The method involves the step of determining whether a candidate agent modulates the activity of an insulin-like growth factor (IGF) or a member of the IGF receptor (IGF1R) family to serve as a modulator of TG-mediated cross-linking, to thereby determine that the candidate agent is a therapeutic agent effective for the treatment of a TG-associated disorder, disease and/or condition.
