Robin Sherrington;Mark Samuels;Marcia MacDonald;Yigal Paul Goldberg
发明人:
Marcia MacDonald,Mark Samuels,Robin Sherrington,Yigal Paul Goldberg
申请号:
US13860810
公开号:
US09278088B2
申请日:
2013.04.11
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to the discovery that mutations in SCN9A are causative of Congenital Indifference to Pain (CIP) in humans. The invention also relates to methods of using compounds small organic compounds to treat pain as well as to predict the effect of analgesic agents in patients, such as those possessing gain of function mutations.