The present invention provides acidic fibroblast growth factor (aFGF) composition, comprising: (i) aFGF of SEQ ID NO: 1, (ii) aFGF of SEQ ID NO: 1 having an N-terminal phosphogluconoylation, (iii) aFGF of SEQ ID NO: 1 having an N-terminal gluconoylation, (iv) aFGF of SEQ ID NO: 2 and (v) aFGF of SEQ ID NO: 3, or a combination thereof. Also provided is a modified acidic fibroblast growth factor (aFGF) which has an N-terminal phosphogluconoylation or gluconoylation.本發明提供酸性纖維母細胞生長因子(acidic fibroblast growth factor;aFGF)組合物,其包含:(i)SEQ ID NO:1之aFGF、(ii)具有N端磷酸葡糖醯化(phosphogluconoylation)之SEQ ID NO:1之aFGF、(iii)具有N端葡糖醯化(gluconoylation)之SEQ ID NO:1之aFGF、(iv)SEQ ID NO:2之aFGF及(v)SEQ ID NO:3之aFGF,或其組合。本發明亦提供經修飾之酸性纖維母細胞生長因子(aFGF),其具有N端磷酸葡糖醯化或葡糖醯化。
