Synthetic compounds and derivatives as modulators of smoking or nicotine ingestion and lung cancer

• 收藏
• 分享

专利权人:

John R. Cashman

发明人:

John R. Cashman

申请号：

US12848619

公开号：

US08609708B2

申请日:

2010.08.02

申请国别(地区):

US

年份:

2013

代理人:

摘要：

Disclosed are nicotine-related compounds that selectively inhibit cytochrome P-450 2A6 (CYP2A6), selectively inhibit cytochrome P-450 2A13 (CYP2A13), and/or selectively modulate a nicotinic acetylcholine receptor (nAChR). Also disclosed are pharmaceutical compositions comprising a compound of the invention, as well as methods of using the pharmaceutical compositions for treating or preventing a disease or disorder associated with nicotine-ingestion, or a disease or disorder amenable to treatment by selective modulation of nAChRs.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/