Daniel Clive Anthony,Sandra Jane Campbell,Francis Joseph Carr,Robin Patrick Choudhury,Benjamin Guy Davis,Timothy David Jones,Nicola Ruth Sibson
申请号:
US14397074
公开号:
US10040854B2
申请日:
2013.04.24
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention provides an antibody or fragment thereof that specifically binds to human endothelial vascular cell adhesion molecule-1 (VCAM-1), wherein the antibody or fragment thereof binds to the extracellular domain of VCAM-1, and wherein the antibody or fragment thereof binds to VCAM-1 when expressed on endothelial cells, wherein the antibody or fragment thereof is a human or humanized antibody, or fragment thereof.