Azaindolinas substituted Compounds, inhibitors of the binding of SMAC Protein inhibitor of Apoptosis Protein (IAP) and / or inhibitors of the binding of Protein to the activated caspase IAP； Pharmaceutical composition that comprises； a method for treating cancer or improve its use； and P For The therapeutic and / or prophylactic Treatment of cancer.

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专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

HOGG, JOAN HEATHER,KESTER ROBERT FRANCIS,LIANG WEILING,YUN WEIYA

申请号：

CL2015000886

公开号：

CL2015000886A1

申请日:

2015.04.08

申请国别(地区):

CL

年份:

2015

代理人:

摘要：

Disclosed are compounds of Formula (I), or pharmaceutically acceptable salts thereof, wherein W, Y, Z, R1, R2, R3 and R4 are as described in this application, and methods of using the compounds in the treatment of cancer.COMPUESTOS DERIVADOS DE 2,3-DIHIDRO-1H-PIRROLO[2,3-B]-PIRIDINA SUSTITUIDOS, INHIBIDORES DE LA UNION DE PROTEINAS SMAC AL INHIBIDOR DE PROTEINAS DE APOPTOSIS (IAP) Y/O INHIBIDORES DE LA UNION DE PROTEINA CASPASA ACTIVADA A LOS IAP； COMPOSICION FARMACEUTICA； UTILES EN EL TRATAMIENTO Y/O PEROFILAXIS DEL CANCER.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/