A method and system are disclosed for assessing the capability of a pilot to operate an aircraft. The system senses the value of at least one operator information parameter for assessing the fitness of the pilot operating the aircraft and at least one aircraft information parameter relating to the position and motion of the aircraft. The operator information parameters include electroencephalogram information, electrocardiogram information, heart rate information, respiratory rate information, eye motion information, eyelid position information, eyelid motion information, expired gas mixture information, blood oxygen content information, blood oxygen saturation information and blood pressure information for the person operating the aircraft, and/or information about actions taken by the person operating the aircraft. Based on these parameters, the system determines if the pilot is capable of properly operating the aircraft and, if not, control of the aircraft is assumed by an alternate source of control which lands the aircraft safely.