CONSTRUCTIONS HYBRIDES ET LEUR UTILISATION POUR PRODUIRE DES ANTICORPS PRESENTANT UNE AFFINITE DE LIAISON ACCRUE POUR LE RECEPTEUR FC ET FONCTION D'EFFECTEUR
The present invention relates to the field of glycosylation engineering ofproteins. More particularly, the present invention relates to nucleic acidmolecules, including fusion constructs, having catalytic activity and the useof same in glycosylation engineering of host cells to generate polypeptideswith improved therapeutic properties, including antibodies with increased Fcreceptor binding and increased effector function.