A drug delivery balloon apparatus 100, where the drug delivery balloon apparatus comprises: at least two lumens, a first lumen 114 and a second lumen 116, a balloon inflation port 102, a guidewire port 110, a drug delivery port 108, an occlusion balloon 104, a drug delivery balloon 106 having an outer surface with a plurality of grooves 140, where the occlusion balloon is disposed between the drug delivery balloon and the balloon inflation port, and the occlusion and drug delivery balloons are in communication with the first lumen, one or more drug delivery channels 120 extending the length of the second lumen, and one or more drug delivery ducts 146 extending from the one or more drug delivery channels to an exterior surface of the second lumen.
