There is provided herein a biopsy probe, comprising an outer elongated hollow body having a distal end configured to penetrate a sampling region, a proximal end and an opening located between said distal end and said proximal end, and an inner needle for obtaining one or more tissue samples, wherein at least a part thereof is located is an inner part of said outer elongated hollow body, wherein in a first configuration thereof, said inner needle extends along an insertions axis of said probe and in a second configuration thereof, at least a part of said inner needle extends through said opening, creating an angle relative to said insertion axis.