Graham Smith;Matthias Eberhard Glaser;Quang-De Nguyen;Eric Ofori Aboagye;Erik Arstad
发明人:
Eric Ofori Aboagye,Graham Smith,Quang-De Nguyen,Erik Arstad,Matthias Eberhard Glaser
申请号：
US13062064
公开号：
US08961930B2
申请日:
2009.09.04
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Isatin 5-sulfonamide derivatives, pharmaceutical compositions comprising the derivatives, their use as molecular imaging agents, their use for the diagnosis or treatment of diseases or disorders associated with dysregulation of apoptosis, methods for synthesizing the derivatives, methods for the molecular imaging of caspase activity and apoptosis, and methods of assessing the therapeutic effect of a test substance on caspase activity are disclosed.
