compound for inhibiting protein aggregation involved in protein aggregation-related diseases and / or neurodegenerative diseases, use thereof, protein aggregate image deposition method and kit for preparing a detectably labeled compound
LUDWIG-MAXMILIANS-UNIVERSITAT MUNCHEN;MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.
发明人:
ANDREI LEONOV,ARMIN GIESE,CHRISTIAN GRIESINGER,HANS KRETZSCHMAR,JENS WAGNER,MARKUS GEISSEN,MARTIN H. GROSCHUP,MATHIAS HABECK,PAUL TAVAN,PETRA FRICK,SERGEY RYAZANOV,THOMAS HIRSCHBERGER,UWE BERTSCH
申请号:
BRPI0913609
公开号:
BRPI0913609A2
申请日:
2009.06.09
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
The present invention relates to a compound represented by formula (E). The present invention also relates to a compound represented by the formula (E) for use in the treatment or prevention of diseases linked to protein aggregation and/or neurodegenerative diseases. Moreover, the present invention relates to pharmaceutical and diagnostic compositions comprising the compound of the invention as well as to a kit. Furthermore, the present invention relates to a method of imaging deposits of aggregated protein. A kit for preparing a detectably labelled compound of the present invention is also disclosed.