Method to identify a population of TR1 cells at Rest, which involves the detection of the expression of cell surface markers CD4, CD25,Disorders and CD62L； isolated population of TR1 cells； method to decrease a population of TR1 cells； Kit for identifying or Isolating a population of TR1 cells at rest and / or activated； fa compositionRmaceutica comprising a population of TR1 cells at rest and / or activated.
The present invention relates to methods for isolating Tr1 cells, resting Tr1 cells and/or activated Tr1 cells, to methods for enriching or depleting a cell population in Tr1 cells, resting Tr1 cells and/or activated Tr1 cells and to methods and kits for treating chronic inflammatory diseases, autoimmune diseases, allergic diseases, cancer and organ transplantation conditions.METODO PARA IDENTIFICAR UNA POBLACIÓN DE CELULAS TR1 EN REPOSO QUE COMPRENDE LA DETECCION DE LA EXPRESION EN LA SUPERFICIE CELULAR DE LOS MARCADORES CD4, CD25, CD127 Y CD62L； POBLACION AISLADA DE CELULAS TR1； METODO PARA DISMINUIR UNA POBLACION DE CELULAS TR1； KIT PARA IDENTIFICAR O AISLAR UNA POBLACION DE CELULAS TR1 EN REPOSO Y/O ACTIVADAS； COMPOSICION FARMACEUTICA QUE COMPRENDE UNA POBLACION DE CELULAS TR1 EN REPOSO Y/O ACTIVADAS.
