The present invention relates generally to a progesterone receptor modulator, or any metabolite thereof for use in the prevention or treatment of androgen mediated diseases characterized in that said progesterone receptor modulator, or any metabolite thereof, is administered to a subject in need thereof.本發明大致上關於用於預防或治療雄性激素仲介之疾病的黃體激素受體調節劑或任何其代謝物,其中該黃體激素受體調節劑或其任一代謝物係被投予有此需要之對象。