A sterile femoral drape intended to be placed over a surgical patient lying on an operating table to isolate the patient during the surgical procedure, the drape comprising a top sheet of bio-impermeable material of a length and width greater than a conventional operating table such that the top sheet fully encompasses the patient and drapes over the lateral side edges and the bottom (foot) edge of the table. Femoral access holes located proximate to the patients groin are provided to allow access to the patients femoral artery during heart catheterizations or other surgical procedures. The drape comprises left and right arm pockets formed underneath the bio-impermeable sheet into which the patients respective left and right arms are inserted. The patients arms being positioned within and supported within the arm pockets, fully isolates the patients arms and hands from the femoral access site, thereby assuring that the patients hands do not contaminate the femoral access site.