Ronald G. Crystal,Martin J. Hicks,Jonathan B. Rosenberg,Bishnu P. De,Stephen M. Kaminsky,Robin L. Davisson
申请号:
US14381534
公开号:
US10093947B2
申请日:
2013.02.25
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention is directed to an adeno-associated virus (AAV) vector which comprises a nucleic acid sequence encoding an antibody or antigen binding fragment that binds to nicotine or a nicotine analog. The invention also is directed to a composition comprising the AAV vector and methods of using the AAV vector to induce an immune response against nicotine in a mammal.