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WT1-ANTIGEN PEPTIDE CONJUGATE VACCINE
专利权人:
INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC.; LTD.;SUMITOMO DAINIPPON PHARMA CO., LTD.;SUMITOMO DAINIPPON PHARMA CO.
发明人:
BAN, HITOSHI,NISHIO, YUKIHIRO,GOTO, MASASHI,NISHIHARA, TOSHIO,TAKANASHI, YOSUKE,LI, CHIANG JIA
申请号:
SG11201507883S
公开号:
SG11201507883SA
申请日:
2014.03.28
申请国别(地区):
SG
年份:
2015
代理人:
摘要:
The present invention provides a compound represented by the formula (1): wherein X a and Y a are each a single bond and the like, cancer antigen peptide A is an MHC class I-restricted WT1 peptide consisting of 7 - 30 amino acid residues, R 1 is a hydrogen atom, a group represented by the formula (2): wherein X b and Y b are each a single bond and the like, cancer antigen peptide B has a sequence different from that of the cancer antigen peptide A, and is an MHC class I-restricted WT1 peptide consisting of 7 - 30 amino acid residues, or cancer antigen peptide C, and cancer antigen peptide C has a sequence different from that of the cancer antigen peptide A, and is an MHC class I-restricted WT1 peptide or an MHC class II-restricted WT1 peptide, consisting of 7 - 30 amino acid residues containing one cysteine residue, or a salt thereof, and the like.
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