The present disclosure is generally directed to compositions that include antibodies,e.g., monoclonal, antibodies, antibody fragments,etc., that specifically bind a CD33polypeptide,e.g., a mammalian CD33 orhuman CD33, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.本揭示案大體上係關於包括特異性結合CD33多肽，例如哺乳動物CD33或人類CD33之抗體，例如單株抗體、抗體片段等的組成物，以及該等組成物在對有需要之個體進行預防、降低風險或治療方面之用途。
