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Application of substituted benzyloxy group-containing ether compounds for the production of antitumor drugs
专利权人:
瀋陽化工研究院有限公司;シノケム・コーポレーション
发明人:
劉長令,関愛瑩,楊小平,柴宝山
申请号:
JP2016537112
公开号:
JP6178010B2
申请日:
2014.08.22
申请国别(地区):
JP
年份:
2017
代理人:
摘要:
Disclosed are applications of substituent benzyloxy group containing ether compounds represented by general formula I for preparing antitumor drugs. The definition of the substituent groups in the formula I are provided in the specification. The compounds having general formula I have desirable antitumor activity, particularly, and have excellent activity against leukemia strain HL-60, lung cancer A549, H157, H460, H520, bladder cancer T24, J82, prostate cancer LNCap, PC-3, rectal cancer HCT8, HCT116, RkO and the like.
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