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MODIFIED RELEASE FORMULATIONS OF PRIDOPIDINE
专利权人:
PRILENIA THERAPEUTICS DEVELOPMENT LTD.
发明人:
Daniella Licht,Ioana Lovinger,Laura Yehudit Guilatt,Merav Bassan
申请号:
US16115105
公开号:
US20190209542A1
申请日:
2018.08.28
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The subject invention provides a modified release solid oral dosage form comprising a therapeutically effective amount of Pridopidine or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable rate controlling excipient, wherein the solid oral dosage form provides an in vivo plasma pridopidine concentration profile having a Mean Cmax of about 1,400 ng/ml or less. The subject invention also provides a method of treating an individual afflicted with a neurodegenerative disease or disease related to dopamine, comprising once daily administration of a modified release solid oral dosage form.
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