Pertussis antigens and use thereof in vaccination

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专利权人:

Philippe Denoel;Cindy Castado;Jan Poolman;Fabrice Godfroid

发明人:

Cindy Castado,Philippe Denoel,Fabrice Godfroid,Jan Poolman

申请号：

US10574297

公开号：

US08574596B2

申请日:

2004.10.01

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The invention provides BASB232 polypeptides and polynucleotides encoding BASB232 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are diagnostic, prophylactic and therapeutic uses. The invention further provides immunogenic compositions comprising a plurality of antigens selected from at least two different categories of antigen, having different functions within Bordetella. Examples of such categories of antigen are autotransporter proteins, iron acquisition proteins, lipoproteins, adhesins and toxins/invasins.

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