HONIGBERG, LEE,VERNER, ERIK,BUGGY, JOSEPH J.,LOURY, DAVID,CHEN, WEI
申请号:
CA2681756
公开号:
CA2681756C
申请日:
2008.03.27
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Described herein are irreversible kinase inhibitor compounds, methods for synthesizing such irreversible inhibitors, and methods for using such irreversible inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate irreversible inhibitor of a protein, including a kinase.