Jie LIU,Zhilong LIN,Bo WEN,Ting TONG,Fen MO,Chao PENG,Qiong SHI
申请号：
US15539709
公开号：
US20180186838A1
申请日:
2014.12.26
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided is a new conotoxin peptide κ-CPTx-btl01. The conotoxin peptide κ-CPTx-btl01 has derivative polypeptide that has an amino acid sequence indicated by SEQ ID NO:1, or has derivative polypeptide that has an amino acid sequence indicated by SEQ ID NO:1 and that is formed after substitution, addition or deletion of one or more amino acids are performed and has original functions. Also provided is polynucleotide for coding the peptide, comprising a constructed body of the polynucleotide, an expression carrier and transformed cells. A peptide preparation method and uses in the treatment of diseases related to a calcium ion channel.
