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Anti-CD70 antibody-drug conjugates and their use for the treatment of cancer and immune disorders
专利权人:
Linda A. Pestano;Cheu-leung Law;Alan F. Wahl;Nathalie Scholler
发明人:
Cheu-leung Law,Alan F. Wahl,Nathalie Scholler,Linda A. Pestano
申请号:
US13485536
公开号:
US08535678B2
申请日:
2012.05.31
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic, immunosuppressive, or other therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of CD70-expressing cancers and immunological disorders, comprising administering to a subject the disclosed pharmaceutical compositions.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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