Linda A. Pestano;Cheu-leung Law;Alan F. Wahl;Nathalie Scholler
发明人:
Cheu-leung Law,Alan F. Wahl,Nathalie Scholler,Linda A. Pestano
申请号:
US13485536
公开号:
US08535678B2
申请日:
2012.05.31
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic, immunosuppressive, or other therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of CD70-expressing cancers and immunological disorders, comprising administering to a subject the disclosed pharmaceutical compositions.