Ji Min Lee,Kyung Ah Kim,Bo Gyou Kim,Young Mi Oh,Saet Byoul Lee,Yun Ju Jeong
申请号：
US13949012
公开号：
US09213031B2
申请日:
2013.07.23
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A method of identifying a cell sample or a subject suitable for treatment with an anti-c-Met antibody or antigen binding fragment thereof that specifically binds to an epitope within a SEMA domain of a c-Met protein by determining a Cbl concentration, a Cbl mutation, and/or a mutation of a site of c-Met for interaction with Cbl in a cell sample from a subject, as well as related compositions and methods.
