Charles N. Serhan;Thomas E. Van Dyke;Nicos A. Petasis
发明人:
Thomas E. Van Dyke,Nicos A. Petasis,Charles N. Serhan
申请号:
US13346543
公开号:
US20120114566A1
申请日:
2012.01.09
申请国别(地区):
US
年份:
2012
代理人:
摘要:
This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease. The invention also provides for methods of treating and preventing oral inflammation, including gingivitis, periodontitis, and other forms of periodontal disease with compositions containing COX-2 inhibitors. Further, the invention provides methods for preventing systemic diseases beyond theoral cavity that are related to periodontal disease using the composition containing lipoxin analogs, COX-2 inhibitors, or both.