A healing device for sealing multiple fistulas, large-opening fistulas, and other wounds and for promoting tissue growth is coupled to tissue surrounding a first tissue opening. The healing device includes a first sealing member placed on a first surface of the tissue over the tissue opening. The healing device also includes a second sealing member placed over a second surface of the tissue over the tissue opening. The healing device may include a growth-enhancing layer located between the first sealing member and the second sealing member. The first sealing member and the second sealing member may sandwich the tissue in between to cover the tissue opening and may be held together with a plurality of securing members that do not exert any force on the tissue.