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EFFECT OF PHOSPHOLIPID COMPOSITION OF RECONSTITUTED HDL ON ITS CHOLESTEROL EFFLUX AND ANTI-INFLAMMATORY PROPERTIES
专利权人:
Kinemed, Inc.;THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Serv
发明人:
Scott TURNER,Anna Schwendeman,Alan Remaley
申请号:
US14815683
公开号:
US20160074473A1
申请日:
2015.07.31
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to peptide-phospholipid formulations, methods of generating these formulations and methods of administering these formulations for treatment. The present disclosure also provides methods for increasing cholesterol efflux, inducing anti-atherosclerotic activity, increasing pre-β HDL, inducing anti-inflammatory activity, inhibiting cytokine release (including cytokines TNF-α, IL-1β, and/or IL-6 or a combination thereof) and increasing cholesterol mobilization and/or esterification by administering the peptide-phospholipid formulations disclosed.
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