Linda Vahdat;Shahin Rafii;Rakhi Naik;Maureen Lane;Vivek Mittal
发明人:
Linda Vahdat,Shahin Rafii,Rakhi Naik,Maureen Lane,Vivek Mittal
申请号:
US14001249
公开号:
US09927444B2
申请日:
2012.02.24
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Methods of determining cancer progression or cancer relapse in a subject at risk for cancer progression or cancer relapse, the methods comprising: obtaining a sample from said subject; measuring the level of VEGFR1+ hematopoietic progenitor cells (HPCs) and/or VEGFR2+ endothelial progenitor cells (EPCs) in said sample; and taking additional samples and conducting additional measurements of HPCs and/or EPCs at one or more later time points. From the measurements, it can be determined whether there is a surge in the level of HPCs and/or EPCs in at least one later measurement, relative to an earlier measurement. A surge in the level of HPCs and/or EPCs indicates increased risk of progression or relapse of said subject's cancer.