HANKUK UNIVERSITY OF FOREIGN STUDIES RESEARCH & BUSINESS FOUNDATION;한국외국어대학교 연구산학협력단
发明人:
KIM, Yong Ae,김용애,KIM, Ji Sun,김지선,JEONG, Ji Ho,정지호
申请号：
KRKR2019/002415
公开号：
WO2020/171274A1
申请日:
2019.02.28
申请国别(地区):
KR
年份:
2020
代理人:
摘要：
The present invention relates to a peptide comprising at least one amino acid sequence selected from the group consisting of the amino acid sequence of SEQ ID NO: 1, the amino acid sequence of SEQ ID NO: 2, the amino acid sequence of SEQ ID NO: 3, and the amino acid sequence of SEQ ID NO: 4, and having prophylactic or therapeutic activity for an inflammatory or autoimmune disease. The present invention also relates to a pharmaceutical or anti-inflammatory composition comprising at least one of the peptides of SEQ ID NOS: 1 to 4 for prophylaxis or therapy of an inflammatory or autoimmune disease. Furthermore, the present invention relates to a use of at least one of the peptides of SEQ ID NOS: 1 to 4 in a therapeutic method for an inflammatory or autoimmune disease or in preparing a therapeutic drug for an inflammatory or autoimmune disease. The peptide comprising any one of the amino acid sequences of SEQ ID NOS: 1 to 4 can significantly inhibit the secretion or expression of inflammatory cytokines such as IL-17, etc. and as such, has a prophylactic or therapeutic activity for an inflammatory or autoimmune disease. Therefore, a composition comprising at least one of the peptides is effective for use in a pharmaceutical composition for prophylaxis or therapy of an inflammatory or autoimmune disease, in a therapeutic method, and in preparing a therapeutic drug, or as an anti-inflammatory composition.La présente invention concerne un peptide comprenant au moins une séquence d'acides aminés choisie dans le groupe constitué par la séquence d'acides aminés SEQ ID NO : 1, la séquence d'acides aminés SEQ ID NO : 2, la séquence d'acides aminés SEQ ID NO : 3, et la séquence d'acides aminés SEQ ID NO : 4, et ayant une activité prophylactique ou thérapeutique contre une maladie inflammatoire ou auto-immune. La présente invention concerne également une composition pharmaceutique ou anti-inflammatoire comprenant au moins l'un des peptides de SEQ ID NO : 1 à 4 destinée à la prophy
