A system to remotely control a transcutaneous electrical nerve stimulation (TENS) device is disclosed. The system includes a TENS control unit where a transceiver of the TENS control unit is configured to receive wireless Bluetooth signals transmitted from a smartphone, and to transmit wireless Bluetooth response signals to the smartphone in response to biofeedback from a user's body. The system also includes a controller configured to transmit electrical stimulus pulses during a treatment session in response to receiving the wireless Bluetooth signals, where the controller is configured to modulate pulse width, frequency, intensity, or any combination thereof, of the electrical stimulus pulses. A graphical user interface is accessible using the smartphone and configured for a user to select desired control commands to transmit to the TENS control unit using the wireless Bluetooth signals, where the control commands determine the electrical stimulus impulses that are applied to the user's body.