John Emmerson Campbell,Philip Jones,Michael Charles Hewitt
申请号：
US14298691
公开号：
US09249162B2
申请日:
2014.06.06
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Provided herein are compounds of formula A-L-B, and pharmaceutically acceptable salts and stereoisomers thereof, whereinA iswherein L, B and R3 are defined herein, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds and compositions provided herein are PDE-10 inhibitors and useful, e.g., for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes.
