Maier Lorizate Nogales;Nerea Huarte Arrayago;Jose Luis Nieva Escandon;Ismael Mingarro Munoz;Enrique Perez Paya;Maria Jose Gomara Elena
发明人:
Jose Luis Nieva Escandon,Maria Jose Gomara Elena,Maier Lorizate Nogales,Nerea Huarte Arrayago,Ismael Mingarro Munoz,Enrique Perez Paya
申请号：
US12159645
公开号：
US08110545B2
申请日:
2006.12.29
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to non-proteolysable oligopeptides that inhibit glycoprotein 41 of the AIDS virus. More specifically, the invention relates to the identification of oligopeptides, particularly hexapeptides, (D), (L) or mixed, preferably D-hexapeptides, which inhibit the binding of a retrovirus to a target cell, thereby providing novel therapies against infection from the human immunodeficiency virus (HIV). The invention also relates to the use of said D-hexapeptides in the form of single components or complex mixtures as prophylactic or therapeutic agents for retroviral infections, especially human immunodeficiency virus type 1 (HIV-1).
