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AMINOPYRAZINE COMPOUNDS WITH A2A ANTAGONIST PROPERTIES
专利权人:
Merck Sharp & Dohme Corp.
发明人:
ZHENG, Junying,WON, Walter,BERLIN, Michael,TING, Pauline,LI, Guoqing,XIAO, Dong,WANG, Hongwu,ASLANIAN, Robert
申请号:
EP20160808075
公开号:
EP3307067(A1)
申请日:
2016.06.06
申请国别(地区):
欧洲专利局
年份:
2018
代理人:
摘要:
Disclosed are compounds having the structure of Formula I, or a pharmaceutically acceptable salt of any thereof, wherein: "Z", R1 and R2 are defined herein, which compounds are believed suitable for use in selectively antagonizing the A2a receptors, for example, those found in high density in the basal ganglia. Such compounds and pharmaceutical formulations are believed to be useful in treatment or management of neurodegenerative diseases, for example, Parkinson's disease, or movement disorders arising from use of certain medications used in the treatment or management of Parkinson's disease.
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中国工程科技知识中心
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