USE OF NICLOSAMIDE IN THE TREATMENT OF P53-DEFICIENT CELLS

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专利权人:

发明人:

Chit Fang CHEOK,Ramesh KUMAR

申请号：

US15761081

公开号：

US20180271809A1

申请日:

2016.09.16

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present disclosure describes a method of treating p53-deficient cells using a niclosamide derivative according to formula (I). The present disclosure further describes a method of treating cancer using the compound according to formula I, as well as methods of screening to identify a compound that selectively target cells wherein p53 is deficient or non-functional.

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中国工程科技知识中心

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http://www.ckcest.cn/home/