The present invention is directed to methods and compositions for the treatment of diverticulosis. It is more specifically directed to compositions including L glutamine its salts or its derivatives and uses of such compositions in the treatment of diverticulosis. In a method aspect the present invention provides a method of treating diverticulosis. The method includes ingestion of 0.05 g/kg body weight to 10.0 g/kg body weight of L glutarnine an L glutamine salt or an L glutamine derivative per day by a person who has diverticulosis.