HOBSON, ADRIAN D.,OH, JASON Z.,MCPHERSON, MICHAEL J.,WAEGELL, WENDY,BRYANT, SHAUGHN H.,HERNANDEZ, AXEL, JR.,IHLE, CLAIRE L.,MARVIN, CHRISTOPHER C.,PERNG, OLIVIA A.,SANTORA, LING C.,WANG, LU
申请号:
CA3081559
公开号:
CA3081559A1
申请日:
2018.11.29
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Provided herein are anti-CD40 antibody drug conjugates comprising a radical of Formula (I), wherein R1, R2, and R3 are as defined herein. Further provided are anti-CD40 antibody drug conjugates of Formula (II), wherein Z, R, AA1, AA2, AA3, m, p, q, n, w, R1, R2, and R3 are as defined herein. Further provided are pharmaceutical compositions and kits thereof, and methods of using same.