Compounds that are inhibitors of at least one of ARG1 and ARG2, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by ARG1 and ARG2 are also described herein.本發明描述係為ARG1及ARG2中至少一者之抑制劑的化合物及含有該等化合物之組合物以及合成該等化合物之方法。本發明亦描述此等化合物及組合物用於治療包括至少部分由ARG1及ARG2介導之癌症及免疫相關病症的一系列不同疾病、病症及病狀的用途。