YOUHEALTH BIOTECH, LIMITED;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人:
ZHANG, KANG,张 康,張 康,HOU, RUI,侯睿,侯睿,LI, GEN,李根,李根
申请号：
TW106138094
公开号：
TW201918556A
申请日:
2017.11.03
申请国别(地区):
TW
年份:
2019
代理人:
摘要：
Disclosed herein are methods and pharmaceutical compositions for the treatment of retinitis pigmentosa, macular degeneration and other retinal conditions by interfering with expression of genes, such as those encoding photoreceptor cell-specific nuclear receptor and neural retina-specific leucine zipper protein, in cells of the eye. These methods and compositions employ nucleic acid based therapies.本文中揭示用於藉由干擾眼睛之細胞中之基因的表現來治療色素性視網膜炎、黃斑變性及其他視網膜病況的方法及醫藥組合物，該等基因係諸如編碼感光體細胞特異性核受體及神經視網膜特異性白胺酸拉鏈蛋白質之彼等基因。此等方法及組合物採用基於核酸之療法。
